Search on: HETEROTRIMERIC G PROTEINS 
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Descriptor English:   Heterotrimeric GTP-Binding Proteins 
Descriptor Spanish:   Proteínas de Unión al GTP Heterotriméricas 
Descriptor Portuguese:   Proteínas Heterotriméricas de Ligação ao GTP 
Synonyms English:   G-Proteins, Heterotrimeric
GTP-Binding Proteins, Heterotrimeric
Heterotrimeric G Proteins
Heterotrimeric GTP Binding Proteins
Heterotrimeric G-Proteins  
Tree Number:   D08.811.277.040.330.300.200
D12.644.360.375
D12.776.157.325.332
D12.776.476.375
D12.776.543.325
Definition English:   GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT. 
Indexing Annotation English:   GEN or unspecified; prefer specifics; DF: HET G PROTEINS
History Note English:   2000 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   34412 
Unique Identifier:   D020962 

Occurrence in VHL:
 

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